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MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies

Abstract Background The idiopathic inflammatory myopathies (IIMs) are heterogeneous autoimmune conditions of skeletal muscle inflammation and weakness. MicroRNAs (miRNAs) are short, non-coding RNA which regulate gene expression of target mRNAs. The aim of this study was to profile miRNA and mRNA in...

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Principais autores: Joanna E. Parkes, Anastasia Thoma, Adam P. Lightfoot, Philip J. Day, Hector Chinoy, Janine A. Lamb
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-06-01
Serier:BMC Rheumatology
Fag:
Idiopathic inflammatory myopathies
Polymyositis
Dermatomyositis
microRNA
RNA sequencing
Online adgang:http://link.springer.com/article/10.1186/s41927-020-00125-8
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