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Brain antibody sequence evaluation (BASE): an easy-to-use software for complete data analysis in single cell immunoglobulin cloning

Abstract Background Repertoire analysis of patient-derived recombinant monoclonal antibodies is an important tool to study the role of B cells in autoimmune diseases of the human brain and beyond. Current protocols for generation of patient-derived recombinant monoclonal antibody libraries are time-...

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Principais autores: S. Momsen Reincke, Harald Prüss, Jakob Kreye
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-10-01
Serier:BMC Bioinformatics
Fag:
Single cell
B cell
Antibody
Immunoglobulin
Sequence analysis
Online adgang:http://link.springer.com/article/10.1186/s12859-020-03741-w
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