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The RNA-binding protein GRSF1 promotes hepatocarcinogenesis via competitively binding to YY1 mRNA with miR-30e-5p

Abstract Background Dysregulation of RNA binding protein (RBP) expression has been confirmed to be causally linked with tumorigenesis. The detailed biological effect and underlying mechanisms of the RBP GRSF1 in hepatocellular carcinoma (HCC) remain unclear. Methods HCC cells with stable knockdown o...

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Bibliografische Detailangaben
Hauptverfasser: Lili Han, Chen Huang, Xiaofei Wang, Dongdong Tong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-01-01
Schriftenreihe:Journal of Experimental & Clinical Cancer Research
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Online-Zugang:https://doi.org/10.1186/s13046-021-02217-w
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