Deletion of Munc18-1 in 5-HT neurons results in rapid degeneration of the 5-HT system and early postnatal lethality.
The serotonin (5-HT) system densely innervates many brain areas and is important for proper brain development. To specifically ablate the 5-HT system we generated mutant mice carrying a floxed Munc18-1 gene and Cre recombinase driven by the 5-HT-specific serotonin reuptake transporter (SERT) promote...
محفوظ في:
| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science (PLoS)
2011-01-01
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| سلاسل: | PLoS ONE |
| الوصول للمادة أونلاين: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22140524/?tool=EBI |
| الوسوم: |
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