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3D-printed lightweight dorsal skin fold chambers from PEEK reduce chamber-related animal distress

Abstract The dorsal skinfold chamber is one of the most important in vivo models for repetitive longitudinal assessment of microcirculation and inflammation. This study aimed to refine this model by introducing a new lightweight chamber made from polyetheretherketone (PEEK). Body weight, burrowing a...

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Principais autores: Wentao Xie, Matthias Lorenz, Friederike Poosch, Rupert Palme, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow, Daniel Strüder
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2022-07-01
Serija:Scientific Reports
Online dostop:https://doi.org/10.1038/s41598-022-13924-5
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