miRNA Enriched in Human Neuroblast Nuclei Bind the MAZ Transcription Factor and Their Precursors Contain the MAZ Consensus Motif

While the cytoplasmic function of microRNA (miRNA) as post-transcriptional regulators of mRNA has been the subject of significant research effort, their activity in the nucleus is less well characterized. Here we use a human neuronal cell model to show that some mature miRNA are preferentially enric...

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Autors principals:	Belinda J. Goldie, Chantel Fitzsimmons, Judith Weidenhofer, Joshua R. Atkins, Dan O. Wang, Murray J. Cairns
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2017-08-01
Col·lecció:	Frontiers in Molecular Neuroscience
Matèries:	nuclear miRNA primate-specific regulation of gene expression neuron differentiation Argonaute proteins splicing
Accés en línia:	http://journal.frontiersin.org/article/10.3389/fnmol.2017.00259/full
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