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Endothelial progenitor cells systemic administration alleviates multi-organ senescence by down-regulating USP7/p300 pathway in chronic obstructive pulmonary disease

Abstract Background Chronic obstructive pulmonary disease (COPD) has impacted approximately 390 million people worldwide and the morbidity is increasing every year. However, due to the poor treatment efficacy of COPD, exploring novel treatment has become the hotpot of study on COPD. Endothelial prog...

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Principais autores: Wenhua Wang, Huaihuai Peng, Menghao Zeng, Jie Liu, Guibin Liang, Zhihui He
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-12-01
coleção:Journal of Translational Medicine
Assuntos:
COPD
Senescence
EPCs
Systemic administration
USP7
p300
Acesso em linha:https://doi.org/10.1186/s12967-023-04735-x
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