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Tick-borne encephalitis virus variants drive distinct TCR repertoire alterations

BackgroundT cells play a crucial role in the adaptive immune response against acute virus infections. The extensive diversity of T cell receptors (TCRs) presents a complex challenge for understanding its implications in immune responses. Investigating the dynamics of the immune response to acute vir...

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Autori principali: Maria A. Salnikova, Ksenia K. Tuchynskaya, Anastasia A. Minervina, Mikhail V. Pogorelyy, Egor V. Okhezin, Galina G. Karganova, Ilgar Z. Mamedov, Yuri B. Lebedev
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-12-01
Serie:Frontiers in Immunology
Soggetti:
T cell
T cell receptor
TCR sequencing
TCR clusters
tick-borne encephalitis (TBE)
TBEV infection
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1663781/full
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