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Efficient Nonviral Stable Transgenesis Mediated by Retroviral Integrase

Efficient transgene delivery is critical for genetic manipulation and therapeutic intervention of target cells. Two well-characterized integrative systems have been described that rely on viral and nonviral vectors. However, use of viral vectors for gene therapy has been associated with several safe...

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Principais autores: Chang-Ying Chiang, Gloria Denise Ligunas, Wei-Chun Chin, Chih-Wen Ni
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-06-01
coleção:Molecular Therapy: Methods & Clinical Development
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2329050120300802
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