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The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans.

During meiotic prophase, the essential events of homolog pairing, synapsis, and recombination are coordinated with meiotic progression to promote fidelity and prevent aneuploidy. The conserved AAA+ ATPase PCH-2 coordinates these events to guarantee crossover assurance and accurate chromosome segrega...

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Autors principals: Anna E Russo, Stefani Giacopazzi, Alison Deshong, Malaika Menon, Valery Ortiz, Kaori M Ego, Kevin D Corbett, Needhi Bhalla
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2023-04-01
Col·lecció:PLoS Genetics
Accés en línia:https://doi.org/10.1371/journal.pgen.1010708
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