High-resolution acoustic ejection mass spectrometry for high-throughput library screening

An approach is described for high-throughput quality assessment of drug candidate libraries using high-resolution acoustic ejection mass spectrometry (AEMS). Sample introduction from 1536-well plates is demonstrated for this application using 2.5 nL acoustically dispensed sample droplets into an Ope...

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Bibliografiske detaljer

Principais autores:	Nate Hoxie, David R. Calabrese, Zina Itkin, Glenn Gomba, Min Shen, Meghav Verma, John S. Janiszewski, Jonathan H. Shrimp, Kelli M. Wilson, Sam Michael, Matthew D. Hall, Lyle Burton, Tom Covey, Chang Liu
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2024-12-01
Serier:	SLAS Technology
Fag:	High-throughput mass spectrometry HTMS Acoustic droplet ejection AEMS AE-MS HT-MS
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2472630324000815
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