Acid and enzymatic hydrolysis of the internal sialic acid residue in native and chemically modified ganglioside GM1
The sialic acid of gangliosides not containing GalNAc (i.e., GM3, GD3) is readily hydrolyzed either enzymatically by sialidases or chemically in acid conditions. On the other hand, in gangliosides having the sialic acid on the internal galactose residue linked to GalNAc (i.e., GM1, GM2) the Neu5Ac i...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
1996-02-01
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| Serier: | Journal of Lipid Research |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S0022227520376240 |
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