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scReadSim: a single-cell RNA-seq and ATAC-seq read simulator

Abstract Benchmarking single-cell RNA-seq (scRNA-seq) and single-cell Assay for Transposase-Accessible Chromatin using sequencing (scATAC-seq) computational tools demands simulators to generate realistic sequencing reads. However, none of the few read simulators aim to mimic real data. To fill this...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Guanao Yan, Dongyuan Song, Jingyi Jessica Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2023-11-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-023-43162-w
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