The inhibitory mechanism of Hal3 on the yeast Ppz1 phosphatase: A mutagenesis analysis
Abstract The Ser/Thr protein phosphatase (PPase) Ppz1 is an enzyme related to the ubiquitous type-1 PPases (PP1c) but found only in fungi. It is regulated by an inhibitory subunit, Hal3, which binds to its catalytic domain. Overexpression of Ppz1 is highly toxic for yeast cells, so its de-regulation...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Nature Portfolio
2017-08-01
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| Serie: | Scientific Reports |
| Accesso online: | https://doi.org/10.1038/s41598-017-09360-5 |
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