Phorbol ester promotes histone H3-Ser10 phosphorylation at the LDL receptor promoter in a protein kinase C-dependent manner

Histone modification is emerging as a major regulatory mechanism for modulating gene expression by altering the accessibility of transcription factors to DNA. This study unravels the relationship between histone H3 modifications and LDL receptor induction, focusing also on routes by which phosphoryl...

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Detalhes bibliográficos

Principais autores:	Wei Huang, Vachaspati Mishra, Sanjay Batra, Ishan Dillon, Kamal D. Mehta
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2004-08-01
coleção:	Journal of Lipid Research
Assuntos:	low density lipoprotein receptor induction histone modification histone H3 on serine 10 mitogen-activated protein kinase protein kinase C
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520313146
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