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Protein transduction domain-mediated influenza NP subunit vaccine generates a potent immune response and protection against influenza virus in mice

The nucleoprotein (NP) is a highly conserved internal protein of the influenza virus, a major target for universal influenza vaccine. Our previous studies have proven NP-based subunit vaccine can provide partial protection in mice. It is reported that the protein transduction domain (PTD) TAT protei...

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Principais autores: Yuan Yin, BeiBei Li, Linting Zhou, Jian Luo, Xueying Liu, Shilei Wang, Qun Lu, Wensong Tan, Ze Chen
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2020-01-01
Serier:Emerging Microbes and Infections
Fag:
Influenza virus
universal vaccine
nucleoprotein
protein transduction domain
cross-protection
Online adgang:https://www.tandfonline.com/doi/10.1080/22221751.2020.1812436
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