Identification of matrix stiffness-related molecular subtypes in HCC via integrating multi-omics analysis and machine learning algorithms

Abstract Background Matrix stiffness is strongly associated with hepatocarcinogenesis and significantly influences the properties of hepatocellular carcinoma (HCC). Investigating matrix stiffness-related signatures provides crucial insights into HCC prognosis and therapeutic response. Methods Multi-...

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主要な著者:	Hanqi Li, Jiayi Zhang, Yu Shi, Huanhuan Wang, Ruida Yang, Shaobo Wu, Yue Li, Xue Yang, Qingguang Liu, Liankang Sun
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-07-01
シリーズ:	Journal of Translational Medicine
主題:	Matrix stiffness Multi-omics Machine learning Signature Hepatocellular carcinoma
オンライン･アクセス:	https://doi.org/10.1186/s12967-025-06733-7
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