Cooperative insulation of regulatory domains by CTCF-dependent physical insulation and promoter competition

Abstract The specificity of gene expression during development requires the insulation of regulatory domains to avoid inappropriate enhancer-gene interactions. In vertebrates, this insulator function is mostly attributed to clusters of CTCF sites located at topologically associating domain (TAD) bou...

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Bibliografische gegevens

Hoofdauteurs:	Thais Ealo, Victor Sanchez-Gaya, Patricia Respuela, María Muñoz-San Martín, Elva Martin-Batista, Endika Haro, Alvaro Rada-Iglesias
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Portfolio 2024-08-01
Reeks:	Nature Communications
Online toegang:	https://doi.org/10.1038/s41467-024-51602-4
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