A prostate-specific membrane antigen targeted small molecule-drug conjugate for efficient prostate cancer therapy at a low dosage

Prostate-specific membrane antigen (PSMA), which is overexpressed in most prostate cancer cells, serves as an ideal target for precision therapy. The clinical utility of the potent chemotherapeutic agent SN38 is hindered by its poor water solubility and systemic toxicity. Herein, we present a novel,...

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Podrobná bibliografie

Hlavní autoři:	Jingjing Zhang, Fanchun Hu, Caiting Deng, Yuhan Ding, Yuchen Yang, Shupeng Han, Jun Liu, Feifei An, Mingsong Shi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-06-01
Edice:	International Journal of Pharmaceutics: X
Témata:	PSMA SMDC SN38 PEG Prostate cancer
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2590156726000149
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