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COVID-19 convalescent plasma boosts early antibody titer and does not influence the adaptive immune response

Multiple randomized, controlled clinical trials have yielded discordant results regarding the efficacy of convalescent plasma in outpatients, with some showing an approximately 2-fold reduction in risk and others showing no effect. We quantified binding and neutralizing antibody levels in 492 of the...

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Bibliografiska uppgifter
Huvudupphov: John F. McDyer, Mahzad Azimpouran, Valerie L. Durkalski-Mauldin, Robert G. Clevenger, Sharon D. Yeatts, Xutao Deng, William Barsan, Robert Silbergleit, Nahed El Kassar, Iulia Popescu, Dimiter Dimitrov, Wei Li, Emily J. Lyons, Sophia C. Lieber, Mars Stone, Frederick K. Korley, Clifton W. Callaway, Larry J. Dumont, Philip J. Norris, for the SIREN-C3PO Investigators
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical investigation 2023-05-01
Serie:JCI Insight
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Länkar:https://doi.org/10.1172/jci.insight.167890
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