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Antibiotic rotation for febrile neutropenic patients with hematological malignancies: clinical significance of antibiotic heterogeneity.

BACKGROUND: Our unit adopted the single administration of cefepime as the initial treatment for febrile episodes in neutropenic patients with hematological malignancies. However, recently, cefepime-resistant gram-negative bacteremia, including those with extended-spectrum β-lactamase (ESBL)-producer...

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Principais autores: Yong Chong, Shinji Shimoda, Hiroko Yakushiji, Yoshikiyo Ito, Toshihiro Miyamoto, Tomohiko Kamimura, Nobuyuki Shimono, Koichi Akashi
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3553165?pdf=render
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