Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet.

Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator (CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity, affecting ~50% of all CF patients, significantly influencing pulmonary function and longevity. Yet, the complex pathogenesis of CFRD remains u...

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Bibliografiske detaljer

Principais autores:	Mauricio Di Fulvio, Marika Bogdani, Myrian Velasco, Timothy S McMillen, Cecilia Ridaura, Lisa Kelly, Mohammed M Almutairi, Shams Kursan, Abu A Sajib, Marcia Hiriart, Lydia Aguilar-Bryan
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2020-01-01
Serier:	PLoS ONE
Online adgang:	https://doi.org/10.1371/journal.pone.0242749
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