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Sustained remission of post-Fontan protein-losing enteropathy achieved by combination therapy with high-dose spironolactone and the somatostatin analogue octreotide: a case report

Abstract Background Protein-losing enteropathy (PLE) is a serious complication affecting approximately 5–12% of patients following the Fontan procedure for congenital heart disease and is associated with high mortality. Its pathophysiology is multifactorial, involving elevated central venous pressur...

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Kaydedildi:
Asıl Yazarlar: Emiko Suzuki, Keisuke Jimbo, Hideo Fukunaga, Masumi Nagata, Kosuke Kashiwagi, Kaori Aoki, Nobuyasu Arai, Eri Miyata, Mitsuyoshi Suzuki, Takahiro Kudo, Hiromichi Shoji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2026-02-01
Seri Bilgileri:BMC Pediatrics
Konular:
Fontan procedure
protein-losing enteropathy
spironolactone
high-dose therapy
octreotide
somatostatin analogue
Online Erişim:https://doi.org/10.1186/s12887-026-06671-3
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