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Treatment of femoral defects in rats with collagen and elastin polymers combined with hydroxyapatite and bone morphogenetic protein

Biomaterials have emerged as promising therapeutic alternatives in clinical conditions in which bone regenerative capacity is limited, whether due to trauma or pathological bone loss. Among these, collagen-based materials, hydroxyapatite (HA), and bone morphogenetic proteins (BMPs) have been extensi...

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Principais autores: Eduardo Gomes Machado, Marina Ribeiro Paulini, Gustavo Andrade Fraga, Ana Maria de Guzzi Plepis, Virgínia da Conceição Amaro Martins, Ewerton Alexandre Galdeano, Renato de Moraes, Marcelo de Azevedo e Souza Munhoz, João Paulo Mardegan Issa, Rogério Leone Buchaim, Daniela Vieira Buchaim, Victor Augusto Ramos Fernandes, Geovane Ribeiro dos Santos, Marcelo Rodrigues da Cunha
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-04-01
Series:Frontiers in Bioengineering and Biotechnology
Assuntos:
biomaterials
bone defects
bone morphogenetic proteins (BMPs)
hydroxyapatite (HA)
tissue engineering
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fbioe.2026.1803995/full
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