Evaluation of the in vitro otoprotective potential of 4-aminopyridine for cisplatin-induced ototoxicity
BackgroundCisplatin, an effective chemotherapy, is a cause of ototoxicity. It enters inner ear cells through Organic Cation Transporter 2 (OCT2). Recently, we identified another cochlear transporter, Multidrug and Toxin Extrusion Protein 1 (MATE1); it allows cisplatin efflux in renal cells. OCT2 and...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Frontiers Media S.A.
2026-03-01
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| Series: | Frontiers in Audiology and Otology |
| Assuntos: | |
| Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fauot.2026.1729137/full |
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