Alternative ergosterol biosynthetic pathways confer antifungal drug resistance in the human pathogens within the Mucor species complex

ABSTRACT Mucormycoses are emerging fungal infections caused by a variety of heterogeneous species within the Mucorales order. Among the Mucor species complex, Mucor circinelloides is the most frequently isolated pathogen in mucormycosis patients and despite its clinical significance, there is an abs...

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Principais autores:	María Isabel Navarro-Mendoza, Carlos Pérez-Arques, Josie Parker, Ziyan Xu, Steven Kelly, Joseph Heitman
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology 2024-08-01
Serija:	mBio
Teme:	genetic tranformation ergosterol antifungal resistance Erg3 Erg6 Mucorales
Online dostop:	https://journals.asm.org/doi/10.1128/mbio.01661-24
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