Oleic acid from cancer-associated fibroblast promotes cancer cell stemness by stearoyl-CoA desaturase under glucose-deficient condition

Abstract Background Cancer-associated fibroblasts (CAFs) coordinate the malignancy of cancer cells via secretory materials. Reprogrammed lipid metabolism and signaling play critical roles in cancer biology. Oleic acid (OA) serves as a source of energy under glucose-deficient conditions, but its func...

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Principais autores:	Sung-Hyun Hwang, Yeseul Yang, Jae-Ha Jung, Yongbaek Kim
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2022-12-01
סדרה:	Cancer Cell International
נושאים:	Cancer-associated fibroblasts Oleic acid Stearoyl-CoA desaturase Glucose starvation Lipid metabolism
גישה מקוונת:	https://doi.org/10.1186/s12935-022-02824-3
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