Curcumin modulates β-catenin stabilization via targeting proteasomal deubiquitinating enzyme USP14☆

Loss of β-catenin homeostasis is tightly associated with human malignancies, modulation of β-catenin stabilization could be an attractive strategy for cancer therapy. In the present study, we demonstrated that an ancient drug curcumin was associated with selective accumulation of phosphorylated β-ca...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Mengzhen Shen, Lizhe Chen, Jie Jiang, Ziye Wang, Qing Gong, Xue Zhang, Xisong Ke, Yi Qu
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2025-06-01
Cyfres:	Pharmacological Research
Pynciau:	Curcumin β-catenin stabilization USP14 proteasome colorectal cancer
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S1043661825001707
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!