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Comparing the impact of sample multiplexing approaches for single-cell RNA-sequencing on downstream analysis using cerebellar organoids

Summary: Multiplexing overcomes limited throughput in single-cell RNA sequencing (scRNA-seq). Commercial strategies include Parse Biosciences combinatorial barcoding (Parse) and 10x Genomics CellPlex with microfluidic capture (10x). It is currently unknown how these techniques differ when characteri...

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Principais autores: Kseniia Sarieva, Theresa Kagermeier, Vladislav Lysenkov, Francesco Castagnetti, Zeynep Yentuer, Katharina Becker, Julia Matilainen, Nicolas Casadei, Simone Mayer
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-02-01
Serier:iScience
Fag:
natural sciences
biological sciences
cellular neuroscience
cell biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004226001550
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