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Functional PET for mapping metabolic dynamics in Parkinson’s disease

Abstract Static [18F]-FDG PET studies have shown characteristic metabolic patterns for Parkinson’s disease (PD). However static PET scans offer only a snapshot of synaptic activity, preventing insights into dynamics of glucose consumption on individual level. In this study, we apply a novel dynamic...

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Autori principali: Vanessa Heinecke, Lilly Machholz, Kenan Steidel, Lenna M. Rüsing, Falk K. Thiemig, Damiano Librizzi, Maya Beckersjürgen, Jennifer Fuchs, Markus Luster, Lars Timmermann, David Pedrosa, Marina C. Ruppert-Junck
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-11-01
Serie:Scientific Reports
Soggetti:
Glucose dynamics
Metabolic variation
Seed-based metabolic connectivity
Neurocognitive networks
Cognitive symptoms
Non-motor symptoms
Accesso online:https://doi.org/10.1038/s41598-025-28456-x
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