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Location of the hydrophobic pocket in the binding site of fentanyl analogs in the m-opioid receptor

Fentanyl is a highly potent and clinically widely used narcotic analgesic. The synthesis of its analogs remains a challenge in an attempt to develop highly se­lective m-opioid receptor agonists with specific pharmacological properties. In this paper, the use of flexible molecular docking of several...

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Autores principales: LJILJANA DOSEN–MICOVIC, MILOVAN IVANOVIC, VUK MICOVIC
Formato: Artigo
Lenguaje:Inglês
Publicado: Serbian Chemical Society 2007-07-01
Colección:Journal of the Serbian Chemical Society
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Acceso en línea:http://www.shd.org.yu/JSCS/Vol72/No7/JSCS_V72_No7-02.pdf
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