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Controlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responses.

Increasing evidence shows that the cancer microenvironment affects both tumorigenesis and the response of cancer to drug treatment. Therefore in vitro models that selectively reflect characteristics of the in vivo environment are greatly needed. Current methods allow us to screen the effect of extri...

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Principais autores: Maria Håkanson, Stefan Kobel, Matthias P Lutolf, Marcus Textor, Edna Cukierman, Mirren Charnley
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2012-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3387021?pdf=render
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