Impact of recombinant expression in Komagataella phaffii on the allergenic properties of the peanut allergen Ara h 2

IntroductionRecombinant allergens are an important diagnostic tool for determining the IgE-sensitization profile of patients, assessing the risk of symptom severity and potential clinical cross-reactivity. In this context, the use of different host cells for recombinant expression must be evaluated...

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Principais autores:	Andrea Wangorsch, Annette Jamin, Sonja Wolfheimer, Melanie Albrecht, Stefan Vieths, Jonas Lidholm, Stephan Scheurer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-12-01
coleção:	Frontiers in Immunology
Assuntos:	peanut allergy 2S albumin Ara h 2 allergen IgE - binding recombinant expression Kex2 endoprotease
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1713823/full
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