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Identification of a novel signature in progression of non-small cell lung cancer based on HdWGCNA and in vitro validation

Abstract Background Lung cancer is the predominant contributor to cancer-induced mortality, with non-small cell lung cancer (NSCLC) constituting the majority. However, the intricacies of tumorigenesis and progression in this context remain incompletely understood. Methods Utilizing single-cell RNA s...

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Principais autores: Kunpeng Zhang, Wenqiang Xia, Yi Li, Bowen Shi, Weiwei Yang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-02-01
coleção:BMC Medical Genomics
Assuntos:
HdWGCNA
Immune microenvironment
Immunotherapy
Non-small cell lung cancer
Prognostic signature
Acesso em linha:https://doi.org/10.1186/s12920-026-02328-3
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