IS4‐FAM, a fluorescent tool to study CXCR4 affinity and competitive antagonism in native cancer cells
Abstract The ability to accurately measure drug‐target interaction is critical for the discovery of new therapeutics. Classical pharmacological bioassays such as radioligand or fluorescent ligand binding assays can define the affinity or Kd of a ligand for a receptor with the lower the Kd, the stron...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Wiley
2024-10-01
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| Seria: | Pharmacology Research & Perspectives |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1002/prp2.70003 |
| Etykiety: |
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