Polymer Complexes of Ofloxacin and Their Antibacterial Activity

To lower the toxicity and to prolong the action of the monofluoroquinolone ofloxacin, its water-soluble polymer complexes were developed. Cationic copolymers of N-vinylpyrrolidone (VP) with 2-aminoethylmethacrylate (2-AEM) and its hydrochloride (2-AEM-HCl), containing 10.9-28.3 mol. % -NH2 or -NH3Cl...

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Bibliografiske detaljer

Principais autores:	E. P. Ananyeva, S. S. Baranov, A. V. Karavaeva, M. S. Borisenko, M. V. Solovskiy, N. V. Zacharova, T. A. Prazdnikova, E. B. Tarabukina
Format:	Artigo
Sprog:	Russo
Udgivet:	LLC "Publishing House OKI" 2020-05-01
Serier:	Антибиотики и Химиотерапия
Fag:	ofloxacin polymer complexes cationic polymers antibacterial activity acute toxicity
Online adgang:	https://www.antibiotics-chemotherapy.ru/jour/article/view/571
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