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Formulation and Evaluation of Prednisolone Sodium Metazoate-Loaded Mucoadhesive Quatsomal Gel for Local Treatment of Recurrent Aphthous Ulcers: Optimization, In Vitro, Ex Vivo, and In Vivo Studies

This study aims to formulate a buccal mucoadhesive gel containing prednisolone sodium metazoate-loaded quatsomes for efficient localized therapy of recurrent aphthous ulcers. Quatsomes were prepared using a varied concentration of quaternary ammonium surfactants (QAS) and cholesterol (CHO). A 2<sup>...

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Principais autores: Ashraf Kassem, Hanan Refai, Mohamed A. El-Nabarawi, Menna M. Abdellatif
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-07-01
Serier:Pharmaceutics
Fag:
recurrent aphthous ulcer
buccal mucoadhesive gel
quatsomes
prednisolone sodium metazoate
Online adgang:https://www.mdpi.com/1999-4923/15/7/1947
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