Antisense-Mediated Suppression of Heparanase Gene Inhibits Melanoma Cell Invasion

Cancer metastasis is a frequent manifestation of malignant melanoma progression. Successful invasion into distant organs by tumor cells must include attachment to microvessel endothelial cells, degradation of basement membranes and extracellular matrix (ECM). Heparan sulfate proteoglycans (HSPG) are...

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Bibliografiske detaljer

Principais autores:	Madhuchhanda Roy, Jane Reiland, Brian P. Murry, Vladimir Chouljenko, Konstantin G. Kousoulas, Dario Marchetti
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2005-03-01
Serier:	Neoplasia: An International Journal for Oncology Research
Fag:	Malignant melanoma heparanase heparan sulfate invasion and metastasis anti-sense gene delivery
Online adgang:	http://www.sciencedirect.com/science/article/pii/S1476558605800260
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