Upregulation of mitoNEET disrupts granulosa cell proliferation, apoptosis and mitochondrial homeostasis : a possible pathogenesis of follicular dysplasia in PCOS

Abstract Background Polycystic ovary syndrome (PCOS), a leading cause of anovulatory infertility, is characterized by arrested follicular development due to imbalanced proliferation and apoptosis of granulosa cells (GCs). The molecular mechanisms of this dysfunction remain unclear. This study explor...

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Detalhes bibliográficos

Principais autores:	Na Liang, Qi Zhu, Xia Wang, Jieyu Cai, Linglin Weng, Mingrui Xue, Xiaoqi Hong, Hongshan Ge
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	Journal of Ovarian Research
Assuntos:	PCOS MitoNEET Cell proliferation Apoptosis Follicular dysplasia
Acesso em linha:	https://doi.org/10.1186/s13048-026-02018-9
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