A new osteogenic protein isolated from Dioscorea opposita Thunb accelerates bone defect healing through the mTOR signaling axis

Delayed bone defect repairs lead to severe health and socioeconomic impacts on patients. Hence, there are increasing demands for medical interventions to promote bone defect healing. Recombinant proteins such as BMP-2 have been recognized as one of the powerful osteogenic substances that promote mes...

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Principais autores:	John Akrofi Kubi, Augustine Suurinobah Brah, Kenneth Man Chee Cheung, Yin Lau Lee, Kai-Fai Lee, Stephen Cho Wing Sze, Wei Qiao, Kelvin Wai-Kwok Yeung
Format:	Artigo
Jezik:	Inglês
Izdano:	KeAi Communications Co., Ltd. 2023-09-01
Serija:	Bioactive Materials
Teme:	Dioscorea spp protein Mesenchymal stem cells (MSCs) Osteoblast differentiation Bone mineral density (BMD) Bone defect repair mTOR signaling pathway
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2452199X23001366
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