Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones

In chronic lymphocytic leukemia, usually a monoclonal disease, multiple productive immunoglobulin heavy chain gene rearrangements are identified sporadically. Prognostication of such cases based on immunoglobulin heavy variable gene mutational status can be problematic, especially if the different r...

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Detalhes bibliográficos

Principais autores:	Karla Plevova, Hana Skuhrova Francova, Katerina Burckova, Yvona Brychtova, Michael Doubek, Sarka Pavlova, Jitka Malcikova, Jiri Mayer, Boris Tichy, Sarka Pospisilova
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Ferrata Storti Foundation 2014-02-01
coleção:	Haematologica
Acesso em linha:	https://haematologica.org/article/view/6933
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