Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting.

<h4>Background</h4>To replicate, lentiviruses such as HIV must integrate DNA copies of their RNA genomes into host cell chromosomes. Lentiviral integration is favored in active transcription units, which allows efficient viral gene expression after integration, but the mechanisms directing integrati...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Heather M Marshall, Keshet Ronen, Charles Berry, Manuel Llano, Heidi Sutherland, Dyana Saenz, Wendy Bickmore, Eric Poeschla, Frederic D Bushman
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2007-12-01
Serier:	PLoS ONE
Online adgang:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001340&type=printable
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!