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Integrin β1 is a key determinant of the expression of angiotensin-converting enzyme 2 (ACE2) in the kidney epithelial cells.

The expression of the angiotensin-converting enzyme 2 (ACE2) is altered in multiple chronic kidney diseases like hypertension and renal fibrosis, where the signaling from the basal membrane proteins is critical for the development and progression of the various pathologies. Integrins are heterodimer...

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Autori principali: Md Saimon Mia, Delowar Hossain, Emerson Woodbury, Sean Kelleher, Riya.J. Palamuttam, Reena Rao, Preston Steen, Yagna PR Jarajapu, Sijo Mathew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2023-06-01
Serie:European Journal of Cell Biology
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Accesso online:http://www.sciencedirect.com/science/article/pii/S0171933523000316
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