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Hypoxia-conditioned mesenchymal stem cells (MSC) exosomes attenuate ultraviolet-B (UVB)-mediated malondialdehyde (MDA) and matrix metalloproteinase-1 (MMP)-1 upregulation in collagen loss models

Aim To investigate the effects of exosome-derived human mesenchymal stem cells (EH-MSCs) on matrix metalloproteinase-1 (MMP)-1 and malondialdehyde (MDA) levels in ultraviolet-B (UVB)-irradiated Wistar rats.Methods The study used a post-test-only control group design with randomized allocation. Thirt...

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Principais autores: Jessica Angelina, Agung Putra, Setyo Trisnadi, Dedy Hermansyah, Eko Setiawan, Titiek Sumarawati, Nur Dina Amalina
Formato: Artigo
Idioma:Inglês
Publicado: Medical Association of Zenica-Doboj Canton 2025-02-01
Series:Medicinski Glasnik
Assuntos:
extracellular matrix
hypoxiainduced factors
oxidative stress
photoaging
stem cell therapy
Acceso en liña:https://medicinskiglasnik.ba/article/2142
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