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Curvularin Isolated From Phoma macrostoma Is an Antagonist of RhlR Quorum Sensing in Pseudomonas aeruginosa

Quorum sensing (QS) is an attractive target for the treatment of multidrug-resistant Pseudomonas aeruginosa, against which new antibiotics are urgently needed. Because LasR is at the top of the QS hierarchy controlling Rhl and PQS systems, most QS inhibitors have been targeted to LasR. However, it h...

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Autori principali: Ha-Young Choi, Duc Dat Le, Won-Gon Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-07-01
Serie:Frontiers in Microbiology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fmicb.2022.913882/full
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