Reduction of brain stem pathology and transient amelioration of early cognitive symptoms in transgenic mice treated with a monoclonal antibody against α-synuclein oligomers/protofibrils
Immunotherapy against alpha-synuclein (α-syn) is a promising novel treatment strategy for Parkinson's disease (PD) and related α-synucleinopathies. We have previously shown that systemic treatment with the monoclonal oligomer/protofibril-selective antibody mAb47 targeting cytotoxic α-syn leads to re...
Guardat en:
| Autors principals: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2023-01-01
|
| Col·lecció: | Aging Brain |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2589958923000233 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|