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N-Hexyl-0-glucosyl sphingosine, an inhibitor of glucosyl ceramide, β-glucosidase

A synthetic analog of glucocerebroside, N-hexyl-0-glucosyl sphingosine, was found to inhibit the glucosidase in rat spleen that hydrolyzes glucocerebroside. At a concentration of 1 μm, the analog inhibited the enzyme by 48%. The mode of action appeared to be competitive, probably aided by tight bind...

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Detaylı Bibliyografya
Asıl Yazarlar: John S. Erickson, Norman S. Radin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 1973-03-01
Seri Bilgileri:Journal of Lipid Research
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S0022227520368991
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