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Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype

Abstract Background Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis; however, the mechanisms by which they contribute to disease progression are not well described. Previous studies demonstrated that rheumatoid arthritis FLS are heterogeneous, and subpopulations with trans...

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Bibliografiske detaljer
Principais autores: Megan M. Simonds, Kathleen E. Sullivan, AnneMarie C. Brescia
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-09-01
Serier:Arthritis Research & Therapy
Fag:
Online adgang:https://doi.org/10.1186/s13075-022-02913-8
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