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Chimeric Antigen Receptor T-Cells in B-Acute Lymphoblastic Leukemia: State of the Art and Future Directions

Use of adoptive T-cell therapy modified with chimeric antigen receptor (CAR-T) has revolutionized treatment of patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (B-ALL). CAR-T cells directed against CD19 antigen have produced response rates as high as 90% in clinical trials...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Uri Greenbaum, Kris Michael Mahadeo, Partow Kebriaei, Elizabeth J. Shpall, Neeraj Y. Saini
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2020-08-01
Rangatū:Frontiers in Oncology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/article/10.3389/fonc.2020.01594/full
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