Tezepelumab in severe asthma: chest computed tomography assessment of airway remodeling and clinical remission

IntroductionSevere asthma is characterized by persistent uncontrolled symptoms despite optimal standard therapy and/or by the need for high-intensity treatment to maintain control. Thymic stromal lymphopoietin (TSLP) is a key innate cytokine that promotes bronchial inflammation in both T2-high and T...

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Detalhes bibliográficos

Principais autores:	Chiara Lupia, Caterina Battaglia, Daniela Pastore, Youngjin Lee, Giovanna Lucia Piazzetta, Emanuela Chiarella, Nadia Lobello, Giovanni Sireno, Alessandro Pullano, Claudia Crimi, Alessandro Vatrella, Francesco Manti, Pier Paolo Arcuri, Domenico Laganà, Girolamo Pelaia, Corrado Pelaia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-01-01
Colecção:	Frontiers in Pharmacology
Assuntos:	chest computed tomography clinical remission mucus plug severe asthma tezepelumab
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1757754/full
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